Butanone 丁酮MSDS

2-Butanone, 99+%

ACC# 95495

Section 1 - Chemical Product and Company Identification MSDS Name: 2-Butanone, 99+%

Catalog Numbers: AC149670000, AC149670010, AC149670025

Synonyms: 2-Butanone; Ethyl methyl ketone; MEK; Methyl ethyl ketone. Company Identification:

Acros Organics N.V.

One Reagent Lane

Fair Lawn, NJ 07410

For information in North America, call: 800-ACROS-01

For emergencies in the US, call CHEMTREC: 800-424-9300

Section 2 - Composition, Information on Ingredients

CAS#Chemical Name Percent EINECS/ELINCS 78-93-3 Methyl Ethyl Ketone >99% 201-159-0

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: colorless liquid. Flash Point: -7 deg C.

Danger! Extremely flammable liquid and vapor. Vapor may cause flash fire. May cause respiratory tract irritation. May cause severe eye and skin irritation with possible burns. May cause central nervous system effects. May cause fetal effects. Target Organs: Central nervous system, eyes, skin, mucous membranes.

Potential Health Effects

Eye: Causes eye irritation. May result in corneal injury.

Skin: May be absorbed through the skin in harmful amounts. Prolonged and/or repeated contact may cause irritation and/or dermatitis.

Ingestion: May cause irritation of the digestive tract. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure.

Inhalation: Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma.Causes respiratory tract irritation. Irritation may lead to chemical pneumonitis and pulmonary edema. May cause numbness in the extremities.

Chronic: Chronic inhalation may cause effects similar to those of acute inhalation. Prolonged or repeated skin contact may cause defatting and dermatitis. Animal studies have reported that fetal effects/abnormalities may occur when maternal toxicity is seen.

Section 4 - First Aid Measures

Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed.

Skin: Get medical aid. Rinse area with large amounts of water for at least 15 minutes. Remove contaminated clothing and shoes.

Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.

Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.

Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors can travel to a source of ignition and flash back. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Flammable Liquid. Can release vapors that form explosive mixtures at temperatures above the flashpoint. Use water spray to keep fire-exposed containers cool. Water may be ineffective. Material is lighter than water and a fire may be spread by the use of water. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. May polymerize explosively when involved in a fire. Containers may explode when heated.

Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Do NOT use straight streams of water. Cool containers with flooding quantities of water until well after fire is out.

Flash Point: -7 deg C ( 19.40 deg F)

Autoignition Temperature: 404 deg C ( 759.20 deg F)

Explosion Limits, Lower:1.4 vol%@200F

Upper: 11.4 vol%@200F

NFPA Rating: (estimated) Health: 1; Flammability: 3; Instability: 0Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8.

Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.

Section 7 - Handling and Storage

Handling: Use only in a well-ventilated area. Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Storage: Keep away from sources of ignition. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.

Section 8 - Exposure Controls, Personal Protection

Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits. Exposure Limits

Chemical Name ACGIH NIOSH OSHA - Final PELs

Methyl Ethyl Ketone 200 ppm TWA; 300

ppm STEL 200 ppm TWA; 590

mg/m3 TWA 3000

ppm IDLH

200 ppm TWA; 590

mg/m3 TWA

OSHA Vacated PELs: Methyl Ethyl Ketone: 200 ppm TWA; 590 mg/m3 TWA Personal Protective Equipment

Eyes: Wear chemical goggles.

Skin: Wear appropriate protective gloves to prevent skin exposure.

Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 orEuropean Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Section 9 - Physical and Chemical Properties Physical State: Liquid

Appearance: colorless

Odor: sweetish odor - alcohol-like

pH: Not available.

Vapor Pressure: 71.2 mm Hg

Vapor Density: 2.5 (Air=1)

Evaporation Rate:2.7 (Ether=1)

Viscosity: 0.42 mPas 15 deg C

Boiling Point: 80 deg C @ 760mm Hg

Freezing/Melting Point:-87 deg C

Decomposition Temperature:Not available.

Solubility: miscible with oils

Specific Gravity/Density:.8050g/cm3

Molecular Formula:C4H8O

Molecular Weight:72.11

Section 10 - Stability and Reactivity

Chemical Stability: Stable at room temperature in closed containers under normal storage and handling conditions.

Conditions to Avoid: Incompatible materials, ignition sources, excess heat. Incompatibilities with Other Materials: Strong oxidizing agents, amines, ammonia, copper, isocyanates, caustics (e.g. ammonia, ammonium hydroxide, calcium hydroxide, potassium hydroxide, sodium hydroxide), chlorosulfonic acid, fuming sulfuric acid, potassium-tert-butoxide, pyridine, chloroform + alkali, hydrogen peroxides + nitric acid, 2-propanol, inorganic acids.

Hazardous Decomposition Products: Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information

RTECS#:

CAS# 78-93-3: EL75000

LD50/LC50:

CAS# 78-93-3:Draize test, rabbit, eye: 80 mg;

Draize test, rabbit, skin: 500 mg/24H Moderate;

Draize test, rabbit, skin: 402 mg/24H Mild;

Inhalation, mouse: LC50 = 32 gm/m3/4H;

Inhalation, rat: LC50 = 23500 mg/m3/8H;

Oral, mouse: LD50 = 3000 mg/kg;

Oral, rat: LD50 = 2737 mg/kg;

Skin, rabbit: LD50 = 80 mg/kg;Carcinogenicity:

CAS# 78-93-3: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No information available.

Teratogenicity: Embryo or Fetus: fetotoxicity, ihl-rat TCLo=1000 ppm. Specific Developmental Abnormalities: craniofacial and urogenital, ihl-rat TCLo=3000

ppm/7H; musculoskeletal, ihl-rat TCLo=1000 ppm.

Reproductive Effects: No information available.

Neurotoxicity: No information available.

Mutagenicity: Sex chromosome loss/non-disjunction: S. cerevisiae 33800 ppm. Other Studies: See actual entry in RTECS for complete information.

Section 12 - Ecological Information

Ecotoxicity: Fish: Fathead Minnow: LC50 = 3220 mg/L; 96 Hr; UnspecifiedFish: Bluegill/Sunfish: LC50 = 1690 mg/L; 96 Hr; UnspecifiedBacteria: Phytobacterium phosphoreum: EC50 = 51.9 mg/L; 25 min; Microtox testBacteria: Phytobacterium phosphoreum: EC50 =3373 mg/L; 30 min; Microtox test Fathead minnow

LC50=3220 mg/L/96H Bluegill TLm=50 to 1690 mg/L/24 to 96H Environmental: Substance evaporates in water with T1/2= 3D (rivers) to 12D (lakes). Substance is not expected to bioconcentrate in aquatic organisms. Physical: Substance photodegrades in air with T1/2 = 2.3 days.

Other: None information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.

RCRA P-Series: None listed.

RCRA U-Series:

CAS# 78-93-3: waste number U159 (Ignitable waste, Toxic waste).Section 14 - Transport Information

US DOT Canada TDG

Shipping Name:ETHYL METHYL KETONE ETHYL METHYL KETONE

Hazard Class: 3 3 UN Number: UN1193 UN1193 Packing Group: II II Additional Info:FLASHPOINT -7 C

Section 15 - Regulatory Information

US FEDERAL

TSCA

CAS# 78-93-3 is listed on the TSCA inventory.

Health & Safety Reporting List

CAS# 78-93-3: Effective 10/4/82, Sunset 10/4/92

Chemical Test Rules

None of the chemicals in this product are under a Chemical Test Rule.

Section 12b

None of the chemicals are listed under TSCA Section 12b.

TSCA Significant New Use Rule

None of the chemicals in this material have a SNUR under TSCA.

CERCLA Hazardous Substances and corresponding RQs

CAS# 78-93-3: 5000 lb final RQ; 2270 kg final RQ

SARA Section 302 Extremely Hazardous Substances

None of the chemicals in this product have a TPQ.

SARA Codes

CAS # 78-93-3: acute, flammable.

Section 313

This material contains Methyl Ethyl Ketone (CAS# 78-93-3, >99%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR

Part 373.

Clean Air Act:

CAS# 78-93-3 is listed as a hazardous air pollutant (HAP).

This material does not contain any Class 1 Ozone depletors.

This material does not contain any Class 2 Ozone depletors.

Clean Water Act:

None of the chemicals in this product are listed as Hazardous Substances under

the CWA.

None of the chemicals in this product are listed as Priority Pollutants under the

CWA.

None of the chemicals in this product are listed as Toxic Pollutants under the CWA.

OSHA:

None of the chemicals in this product are considered highly hazardous by OSHA. STATE

CAS# 78-93-3 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Minnesota, Massachusetts.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed. European/International Regulations

European Labeling in Accordance with EC Directives

Hazard Symbols:

XI F

Risk Phrases:

R 11 Highly flammable.

R 36 Irritating to eyes.

R 66 Repeated exposure may cause skin dryness or cracking.

R 67 Vapours may cause drowsiness and dizziness.

Safety Phrases:

S 16 Keep away from sources of ignition - No smoking.

S 9 Keep container in a well-ventilated place.

WGK (Water Danger/Protection)

CAS# 78-93-3: 1

Canada - DSL/NDSL

CAS# 78-93-3 is listed on Canada's DSL List.

Canada - WHMIS

This product has a WHMIS classification of B2, D2A.

Canadian Ingredient Disclosure List

CAS# 78-93-3 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 4/27/1999

Revision #4 Date: 3/18/2003

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.